Comparing Collagen Leaders: How Sisel International Emerges As A Strong Alternative To Modere

Collagen has become one of the most sought-after supplements in the wellness industry, recognized for its potential to support skin elasticity, joint health, and overall vitality. In recent years, consumers have increasingly looked for products that align with their expectations for clean sourcing and scientific credibility.

Among the companies that once shaped this movement was Modere, a brand that gained significant attention for its collagen offerings and commitment to lifestyle wellness.

With Modere’s closure, many consumers have been left searching for alternatives that provide the same level of trust and quality. At the same time,new companies are stepping into the spotlight, and well-established companies offer innovative approaches to collagen formulation.

One of well-known, reputable companies is Sisel International, a brand emphasizing science-backed solutions and advanced product development. This comparison aims to take a balanced look at how Modere built its reputation and how Sisel has long been as a strong alternative.

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Why Modere Gained Traction

Modere established itself as a trusted brand within the health and wellness community by positioning its products around clean ingredients, transparency, and lifestyle appeal. The company became particularly well known for its use of BioCell Collagen®, a patented ingredient blend combining hydrolyzed collagen type II peptides with chondroitin sulfate and hyaluronic acid.

This formulation appealed to consumers interested in addressing not just one area of health but a broader range of benefits, including skin hydration, joint support, and healthy connective tissue.

Beyond ingredients, Modere’s branding also played a role in its rise. The company leaned into a “live clean” philosophy that resonated with wellness-minded buyers seeking products free from unnecessary additives. Its emphasis on community engagement and consistent marketing across social platforms helped create a strong base of loyal customers.

For many, Modere became synonymous with accessible collagen supplementation, and the brand was seen as a pioneer in making advanced formulations approachable to everyday consumers.

The Shift: What Happens When A Brand Closes

When a well-established wellness company closes its doors, it leaves more than just a gap in product availability; it disrupts consumer trust. For individuals who had integrated Modere’s collagen into their daily routines, the sudden absence created uncertainty about where to turn next.

This kind of disruption highlights a broader issue in the supplement industry: consumers want stability and assurance that their chosen products will remain available for long-term use.

The closure also opened space for other companies to step forward. It created an opportunity for brands with a proven commitment to research, quality, and consistency to attract former Modere customers. As buyers reconsider their options, they are placing greater emphasis on science-driven innovation and transparent formulation practices. These qualities are increasingly becoming benchmarks for trust in the collagen marketplace.

Enter Sisel International: A Science-Driven Alternative

While Modere earned recognition for its collagen offerings, Sisel International has long been a brand that brings a distinctly science-first approach to supplementation. Founded by industry veterans Tom Mower Sr. and Tom Mower Jr., Sisel’s mission has centered on formulating products that combine cutting-edge research with a commitment to purity and efficacy.

Sisel International’s collagen blends go beyond the basics by incorporating not only high-quality collagen peptides but also supportive ingredients designed to enhance absorption and effectiveness.

By emphasizing bioavailability, the body’s ability to use nutrients efficiently, Sisel addresses one of the key concerns often raised in collagen supplementation. This focus ensures that consumers are not simply taking a product but are more likely to experience its intended benefits.

What also sets Sisel apart is its dedication to continuous innovation. The company not only prioritizes developing advanced formulations that meet the demands of today’s wellness-focused consumers, whether their goals are improved skin elasticity, stronger hair and nails, or joint support, but also benefits from having an integrated manufacturing model.

By overseeing formulation, testing, and production under one system, Sisel maintains tighter control over quality and consistency than brands that outsource. For individuals seeking a stable and innovative option in the wake of Modere’s closure, Sisel represents more than just an alternative; it reflects the next step forward in the evolution of collagen supplementation.

Comparing the Formulas: Modere vs. Sisel

When comparing Modere and Sisel International, the distinctions come into focus through their ingredients, formulation strategies, and brand philosophies.

Ingredients And Formulations

Modere: Best known for its use of BioCell Collagen®, a proprietary blend that combined collagen Type II with hyaluronic acid and chondroitin sulfate. This formulation emphasized skin hydration and joint comfort. However, collagen Types I and III, missing from the BioCell formulas, are the types needed to support skin, hair, and nails.
Sisel International: Unlike BioCell that includes only one source of collagen, Sisel’s CollagenB3 is formulated with collagen Types I and III to strengthen hair, skin, and nails, and with collagen Type II for bone and joint health. This formula is also paired with additional supportive compounds such as MCT oil, synergistic nutrients, and cofactors that aid absorption. This results in a formula designed for both immediate and long-term benefits for beauty, body, and brain.

Benefits

Modere: Customers valued improvements in skin appearance, joint flexibility, and overall wellness support.
Sisel International: In addition to targeting skin, hair, and nail health, Sisel’s approach extends to enhancing bioavailability through the use of cofactors – substances that facilitate biological chemical reactions and are important for collagen synthesis – maximizing the body’s ability to fully utilize collagen. This positions CollagenB3 as both comprehensive and highly efficient.

Approach

Modere: Framed collagen within a lifestyle brand identity, emphasizing clean living and accessibility.
Sisel International: Leans into a research-driven narrative, focusing on innovation, advanced science, and consistent quality assurance.

Taken together, these points illustrate how Modere established a foundation for collagen supplementation in the consumer market, while Sisel has advanced that foundation with greater emphasis on science, innovation, and product efficacy. For consumers transitioning from Modere, Sisel offers a modernized solution that reflects today’s demand for both performance and transparency.

Consumer Considerations: What To Look For In Collagen Supplements

For those seeking a collagen product today, there are several factors to consider when evaluating brands and formulas. Ingredient quality is critical; consumers should look for hydrolyzed or peptide forms of collagen that the body can absorb effectively. The inclusion of synergistic compounds, such as hyaluronic acid, vitamins, or oils that support absorption, can further enhance results.

The types of collagen are key elements in a formulation. Types I and III are essential for skin, hair, and nails, and Type II is best for joint and cartilage support. A comprehensive formulation that includes all three types of collagen is essential for full body support.

Also critical is the presence of cofactors. A cofactor is a substance, often derived from vitamins, that is required for an enzyme to function properly. Vitamin C specifically, is indispensable for the production of collagen, impacting connective tissue, strength, elasticity, and ability to heal.

Another consideration is the form of a collagen product. Powdered formulations like Sisel’s CollgenB3 contain a higher amount of collagen, various types of collagen, and are more versatile and economical. While liquids like BioCell could potentially be more convenient, they don’t typically contain different types, or the quantities needed to produce results. Liquid collagen can typically be overpriced, as you’re mainly paying for water.

Another important factor is transparency. Clear labeling, information about sourcing, and evidence of research-backed development can help consumers make informed decisions. Since collagen supplementation is often a long-term commitment, it is also wise to choose a brand with a track record of consistency and product availability.

Sisel International meets these benchmarks by emphasizing both science and stability. While the company is one of many options in a growing marketplace, its commitment to advanced research and thoughtful formulation makes it an appealing choice for those looking to replace or upgrade from products like Modere’s collagen offerings.

The Bigger Picture: Innovation In The Collagen Market

The collagen marketplace has expanded rapidly, with new innovations shaping how consumers view supplementation. Beyond traditional powders and capsules, companies are introducing ready-to-drink beverages, multi-functional blends, and formulations that combine collagen with vitamins, minerals, or plant-based extracts.

These advancements reflect the growing expectation that wellness products should provide comprehensive benefits rather than focus on a single outcome.

At the same time, clean-label demands remain high. Consumers want products that are effective without unnecessary additives, and they are increasingly drawn to companies that invest in research and transparency. This shift is raising the bar for all brands competing in the space.

Sisel International’s emphasis on science-driven development places it within this broader movement. By aligning with consumer priorities, bioavailability, multi-functionality, and innovation, Sisel positions itself at the forefront of the collagen category, offering a solution that resonates with today’s wellness-minded buyers.

A Successor To Modere’s Legacy

The closure of Modere left many loyal customers without a trusted source for collagen, but it also created an opportunity to reevaluate what matters most in supplementation. Consumers are no longer just searching for a replacement; they want an option that delivers advanced science, consistent availability, and meaningful results.

Sisel International has long been a brand capable of meeting those expectations. With its research-focused approach, innovative formulations, and commitment to quality, Sisel offers more than continuity; it offers progression. For individuals who once relied on Modere, Sisel stands as a strong successor, ensuring that the benefits of collagen remain accessible while advancing the conversation toward the next generation of wellness solutions.